💖

Big List of Meaningful Projects (draft in progress)

This list is the most up-to-date sheet I have of important, meaningful, high-impact projects or causes. It incorporates the awesome list from Cause Prioritization Wiki, a list I found on EA Forum, and a bunch of items I added during a workshop I organized in 2012.

Next steps for this list (notes to myself):

Goals for this list:

Measuring Impact

Visualizations

Description of categories
Megaprojects for example:
Meaningful Projects - 2021 Projects

Meaningful Projects - 2021 Projects

Highest Impact

4 views

Highest Impact

Table

category

Cause Prioritization

Project
Weighted Sum
Source
notes
Neglected
Scale (direct impact on creating happier lives, reducing suffering)
Probability of being solved
Number of lives affected, if it worked
Category
598.5
mla

9
9.5
7
0
AI
560
mla

If everything else takes too long or die in an accident, this is our "Pause"

10
8
7
0
CryoHealth ImprovingSocial inspiration
560
mla

10
8
7
0
Science
480
mla

6
10
8
1e+50
AI
400
mla

8
10
5
0
Nanotech
343
mla

7
7
7
0
Nanotech
336
mla

6
8
7
0
Upload
336
mla

7
8
6
0
Bio Improving body fixing bodyCommunication
280
mla

5
8
7
0
AI
252
mla

3D, non-destructive, Atomic resolution microscopy, of full volume samples, real-time

7
9
4
0
Science
245
mla

5
7
7
0
Computing
240
mla

6
10
4
0
Upload
240

4
10
6
Understanding Reality
225
mla

5
9
5
0
Bio Improving body fixing body
180
mla

4
5
9
0
Science
180
mla

4
9
5
0
Bio Improving body fixing body
105
mla

3
5
7
0
Science
0
mla

0
5
0
0
Science
0
mla

Platform to let software developers loose programming synthetic biological organisms

0
2
0
0
Bio Improving body fixing body
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0

5
3
Wellbeing
0
mla

0
0
0
0
PolicySocietal (large scale population policies)PoliticsCoordinationInfo Gathering
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
WaterFoodSocietal (large scale population policies)
0
EA Forum

0
0
0
0
PolicyAIBioriskX-risks
0
EA Forum

0
0
0
0
Global Priorities
0
EA Forum

0
0
0
0
Food
0
EA Forum

0
0
0
0
Coordination
0
EA Forum

0
0
0
0
Water
0
EA Forum

0
0
0
0
EA cause
0
from cause prioritization website

7
3
0
0
Productivity
0
from cause prioritization website

0
0
0
0
X-risks
0
from cause prioritization website

0
0
0
0
Coordination
0
from cause prioritization website

0
0
0
0
Global Priorities
0
mla

Solving cell sorting or science problems, Many problems are data problems. But the scientists are specialists in their own field, rather than AI, Academic labs could use as service. Subscription basis, Software and hardware service

0
6
0
0
AI
0
mla

0
1
0
0
AI
0
from cause prioritization website

0
0
0
0
0
mla

0
7
6
0
AI
0
mla

0
1
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

0
3
0
0
Science
0
mla

0
6
0
0
Energy
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
Science
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
X-risksBiorisk
0
mla

0
4
0
0
Bio Improving body fixing body
0
mla

0
2
0
0
Bio Improving body fixing body
0
mla

0
0
0
0
Societal (large scale population policies)Bio Improving body fixing body
0
mla

0
0
0
0
antifragility
0
from cause prioritization website

0
0
0
0
X-risksEnvironment
0
from cause prioritization website

0
0
0
0
Environment
0
from cause prioritization website

0
0
0
0
Societal (large scale population policies)Social inspiration
0
mla

0
5
0
0
0
from cause prioritization website

0
0
0
0
ProductivitySocietal (large scale population policies)
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
EA Forum

0
0
0
0
Info Gathering
0
mla

UPLC that takes disposable slides

0
4
0
0
Bio Improving body fixing body
0
mla

Amazon is trying to maximize sales and so doesn't give you the best selections for you

0
1
0
0
AI
0
mla

0
4
0
0
Energy
0
mla

0
0
0
0
0
mla

0
0
0
0
sensing recording tracking
0
from cause prioritization website

0
0
0
0
0

0
mla

interface for interacting with computer, Recording what I see

0
2
0
0
sensing recording tracking
0
mla

0
0
0
0
0
mla

"make an intro to Alton and Christine", Pull info from web, and emails

0
3
0
0
AI
0
EA Forum

0
0
0
0
International Development
0
mla

0
0
0
0
0
mla

0
8
4
0
Science
0
mla

0
0
0
0
Environment
0
from cause prioritization website

0
0
0
0
Health ImprovingPreventing DeathBio Improving body fixing bodyBiorisk
0
from cause prioritization website

0
0
0
0
Health ImprovingWellbeing
0
from cause prioritization website

0
0
0
0
Societal (large scale population policies)
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
X-risks
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
0
mla

General method for filtering out unwanted cells or systemic factors. Many specific applications to start on.

0
4
0
0
Bio Improving body fixing body
0
mla

Non-integrating delivery method with lots of near-term therapeutic potential.

0
4
0
0
Bio Improving body fixing body
0
mla

0
0
0
0
Bio Improving body fixing bodyComputing
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0

Coordination
0

0

0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
1
0
0
0

0
from cause prioritization website

0
0
0
0
0
mla

0
6
0
0
Nanotech
0
from cause prioritization website

0
0
0
0
0
mla

0
1
0
0
Bio Improving body fixing body
0
mla

How are you doing now? If you can measure it, you can affect and experiment with things to improve it

0
6
7
0
Productivity
0
mla

better at accomplishing their goals (writing, scientific method were good ones already)

0
6
5
0
Productivity
0
mla

0
3
0
0
sensing recording tracking
0
mla

0
1
0
0
sensing recording tracking
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
Productivity
0
mla

0
3
0
0
Social inspiration
0
from cause prioritization website

0
0
0
0
0
mla

0
1
0
0
Societal (large scale population policies)
0
from cause prioritization website

0
0
0
0
0
mla

Toe-hold in real stem cell medicine. Treat conditions where bone marrow is damaged (chemotherapy, radiation)

0
5
0
0
Bio Improving body fixing body
0
from cause prioritization website

0
3
0
0
International DevelopmentCoordination
0
mla

Taskrabbit for AI, Odesk, Instead of SAS, AIAS

0
6
0
0
AI
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

0
6
0
0
Energy
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

Grow clones for parabiosis and replacement parts

0
4
0
0
Bio Improving body fixing bodyHealth Improving
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0

0
mla

0
1
0
0
Bio Improving body fixing body
0
mla

0
1
0
0
AI
0
mla

0
3
0
0
Social inspiration
0
mla

0
1
0
0
sensing recording tracking
0
mla

0
4
0
0
Nanotech
0
mla

0
3
0
0
Social inspiration
0
mla

0
5
0
0
CommunicationProductivity
0
mla

0
0
0
0
0
mla

0
1
0
0
Science
0
mla

We could face these challenges and opportunities more effectively by preparing for specific challenges and opportunities (such as nuclear security and climate change in the past and present, and advances in synthetic biology and artificial intelligence in the future), or by enhancing humanity’s general capacities to deal with these challenges and opportunities when we face them (through higher rates of economic growth, improved political coordination, improved use of information and decision-making for individuals and groups, and increases in education and human capital).

0
2
0
0
Societal (large scale population policies)
0
mla

0
0
0
0
0
mla

0
4
0
0
Bio Improving body fixing body
0
mla

0
1
0
0
Science
0
mla

instructions on the moon or straight lines on earth

0
0
0
0
0
mla

0
0
0
0
0
mla

0
1
0
0
Science
0
mla

0
2
0
0
Science
0
mla

0
4
0
0
Societal (large scale population policies)
0
mla

0
3
0
0
AI
0
mla

- manipulate the physical world from a distance as if you were there

0
4
0
0
CommunicationProductivity
0
mla

0
7
5
0
Computing
0
mla

0
3
0
0
Bio Improving body fixing body
0
mla

0
6
0
0
Science
0
mla

0
5
0
0
Societal (large scale population policies)
0
mla

0
6
0
0
Productivity
0
mla

Major drawbacks to oligo synthesis are error rate and write length. This solves one of them.

0
3
0
0
Bio Improving body fixing body
0
mla

0
7
5
0
Science
0
mla

some nootropic that improve cognition, learning ,and memory

0
6
6
0
Productivity
0
mla

0
1
0
0
0
mla

0
3
0
0
Social inspiration
0
mla

0
6
0
0
Productivity
0
mla

0
6
0
0
Science
0
mla

0
0
0
0
EnvironmentCreating More Lives Worth Living
0
mla

the movement of matter across space, with low cost

0
10
1
0
Science
0
mla

Connecting notes

0
5
0
0
AIProductivity
0
mla

0
6
0
0
Computing
0
mla

0
6
0
0
Nanotech
0
mla

politics: the set of activities that are associated with making decisions in groups, or other forms of power relations between individuals, such as the distribution of resources or status. Experiments would be to find better forms of widespread decisionmaking

0
7
0
0
PoliticsCoordination
0
mla

0
1
0
0
Bio Improving body fixing body
0
mla

Would up average lifespan (but wouldn't help those not obese)

0
2
0
0
Bio Improving body fixing body
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

0
3
0
0
AI
0
mla

0
4
0
0
Societal (large scale population policies)
0
from cause prioritization website

0
1
0
0
0
mla

0
0
0
0
Environment
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

Improve silicon valley culture, Good work culture that retains and attracts smart people, Certification for others, Invest in the client, Could have rating system, "96 points on GoodWork" or "GoodWork certified company culture", Could list companies that are GoodWork certified.

0
2
0
0
Societal (large scale population policies)
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
AI
0
from cause prioritization website

https://www.lesswrong.com/posts/cmiRk9XtT9Psnd3Yr/movable-housing-for-scalable-cities

0
0
0
0
0
mla

0
0
0
0
0
mla

1um resolution

0
6
0
0
Science
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

0
5
0
0
Energy
0
mla

0
6
0
0
Nanotech
0
mla

0
4
0
0
Societal (large scale population policies)
0
mla

Stock picking using NLP, Not Algorithmic trading

0
1
0
0
AI
0
from cause prioritization website

0
0
0
0
0
mla

Convince others to work on Solving the Problem of Death

0
3
0
0
Social inspiration
0
from cause prioritization website

0
0
0
0
0
mla

0
1
0
0
Societal (large scale population policies)
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

0
7
6
0
Science
0
mla

0
4
0
0
Societal (large scale population policies)
0
mla

0
4
0
0
Societal (large scale population policies)
0
mla

0
0
0
0
Wellbeing
0
from cause prioritization website

0
0
0
0
0
mla

replace expensive and bulky instruments, have a general purpose chip readers

0
3
0
0
Bio Improving body fixing body
0
mla

0
0
0
0
Societal (large scale population policies)Coordination
0
mla

Go on a trip, come back in the future when aging has hopefully been cured. Definitely Reversible

0
8
4
0
ScienceHealth ImprovingPreventing Death
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

0
7
0
0
PoliticsPreventing DeathX-risksBioriskCoordination
0
mla

0
3
0
0
Social inspiration
0
mla

0
6
0
0
Science
0
mla

0
6
0
0
Productivity
0
mla

- Store ALL data, make it quickly searchable (cooperate with Google)

0
4
0
0
AI
0
mla

0
0
0
0
0
mla

0
6
0
0
Politics
0
mla

0
3
0
0
Productivity
0
mla

Gives people hope that the future can be great and wonderful, examples: Jason Silva, Foresight youth outreach, Stephen Pinker, Greg Egan, Eliezer , Ray Kurzweil, Brad Templeton, Peter Diamandes, Christine Peterson

0
2
0
0
Social inspiration
0
mla

0
4
0
0
Societal (large scale population policies)
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
0
mla

0
0
0
0
0
mla

0
0
0.001
0
CoordinationSocial inspiration
0
mla

0
0
0
0
Health ImprovingEnvironment
0
mla

0
6
0
0
Energy
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

0
2
0
0
Bio Improving body fixing body
0
mla

0
6
0
0
Nanotech
0
mla

0
6
0
0
Bio Improving body fixing body
0
mla

0
6
0
0
Productivity
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

0
4
0
0
Bio Improving body fixing body
0
mla

0
4
0
0
Bio Improving body fixing body
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

Heading toward digital brain, Dynamic weights, Pretrained chips

0
5
0
0
Computing
0
mla

Fast imaging of biological samples. Brain connectomes for AI research.

0
4
0
0
Science
0
mla

0
1
0
0
Societal (large scale population policies)
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
0
mla

0
8
4
0
Science
0
mla

similar to superforecasters book

0
6
0
0
Productivity
0
mla

0
3
0
0
sensing recording tracking
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
0
mla

0
0
0
0
EnvironmentBioriskX-risksantifragilityFood
0
from cause prioritization website

0
0
0
0
0
mla

Convert sound to rf signals for hearing a room really well, http://www.gvrtrade.com/media/13786fff732d9eeffff80017f000101.pdf

0
1
0
0
sensing recording tracking
0
mla

movement of matter across time

0
10
1
0
Science
0
mla

Context sensitive and personalized therapeutics. Can effect actions in vivo very specifically based on sequences present.

0
6
0
0
Bio Improving body fixing body
0
mla

0
4
0
0
Energy
0
from cause prioritization website

0
0
0
0
0
mla

0
4
0
0
Bio Improving body fixing body
0
mla

0
5
0
0
Science
0
from cause prioritization website

0
0
0
0
0
mla

tools to visualize and interact with information, Brain-sensor interfaces

0
6
0
0
CommunicationProductivity
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
AI
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

Lipofuscin accumulates slowly. Exocytosis could prevent accumulation without toxic effects.

0
4
0
0
Bio Improving body fixing body
0
mla

0
2
0
0
Societal (large scale population policies)
0
from cause prioritization website

0
0
0
0
0
from cause prioritization website

0
0
0
0
0
mla

0
0
0
0
0
mla

0
7
5
0
Social inspiration
0
from cause prioritization website

0
0
0
0
0
mla

Non-integrating delivery method with powerful long term potential.

0
4
0
0
Bio Improving body fixing body
0
mla

0
6
0
0
Computing